АЛЬПИНИЯ ЛЕКАРСТВЕННАЯ (ALPINIA OFFICINARUM).

ПУБЛИКАЦИЯ 3: БИОЛОГИЧЕСКОЕ ДЕЙСТВИЕ, ПРИМЕНЕНИЕ В ТРАДИЦИОННОЙ МЕДИЦИНЕ И СОВРЕМЕННОЙ МИРОВОЙ МЕДИКО-ФАРМАЦЕВТИЧЕСКОЙ ПРАКТИКЕ

Авторы

  • Татьяна Леонидовна Киселева Профессиональная ассоциация натуротерапевтов (г. Москва)

Ключевые слова:

традиционная медицина, альпиния лекарственная, Alpinia officinarum, флавоноиды, диарилгептаноиды, фенилпропаноиды, терпены, аддукты ДАГ-терпеновой природы, противовирусное действие, противоопухолевое действие, противомикробное действие, антиоксидантное действие, противовоспалительное действие, нейропротективное действие

Аннотация

Проведенное информационно-аналитическое исследование позволило установить доказанную эффективность и безопасность экстрактов корневищ Alpinia officinarum. Выявлены работы, описывающие механизмы действия БАВ а. лекарственной, а также процессы, обусловливающие противоопухолевый и некоторые другие установленные биологические эффекты. Показано, что наряду с высокой эффективностью некоторые изученные БАВ проявляют селективность, что позволяет считать их перспективными источниками для создания натуральных ЛС, БАД к пище и СПП. Токсические эффекты не выявлены.
Основными группами БАВ, ответственными за широкий спектр фармакотерапевтического действия корневищ малого галангала, можно считать фенолы (флавоноиды, диарилгептаноиды (ДАГ), фенилпропаноиды), терпены, фитостерины и аддукты ДАГ-терпеновой природы. Фенольная фракция, полученная с помощью различных растворителей, как и отдельные БАВ, включая аддукты ДАГ и терпенов, проявляют выраженное антипролиферативное, антиоксидантное, противовоспалительное, противовирусное, нейропротективное, антиостеопоротическое, противоязвенное, антигиперлипидемическое действие. Терпены (в том числе дитерпены), в основном, ответственны за противомикробное, противовоспалительное, антипролиферативное, противовирусное действие.
Полученные результаты свидетельствуют о высоком нутрицевтическом потенциале и хороших перспективах применения альпинии лекарственной в мировой медикофармацевтической практике в качестве источника ЛС, БАД к пище и СПП.

Биография автора

Татьяна Леонидовна Киселева, Профессиональная ассоциация натуротерапевтов (г. Москва)

Д.фарм.н., профессор, директор НИЦ-президент НО «Профессиональная ассоциация натуротерапевтов»

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Опубликован

2020-12-31

Как цитировать

Киселева, Т. Л. «АЛЬПИНИЯ ЛЕКАРСТВЕННАЯ (ALPINIA OFFICINARUM).: ПУБЛИКАЦИЯ 3: БИОЛОГИЧЕСКОЕ ДЕЙСТВИЕ, ПРИМЕНЕНИЕ В ТРАДИЦИОННОЙ МЕДИЦИНЕ И СОВРЕМЕННОЙ МИРОВОЙ МЕДИКО-ФАРМАЦЕВТИЧЕСКОЙ ПРАКТИКЕ». Традиционная медицина, вып. 4(63) 2020, декабрь 2020 г., сс. 15-46, http://www.tradmed.ru/index.php/tm/article/view/1532.

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