АНТИБАКТЕРИАЛЬНАЯ АКТИВНОСТЬ КУРКУМЫ ДЛИННОЙ (CURCUMA LONGA L.)

Т.А. Смирнова; Ю.А. Смирнов; В.Г. Жуховицкий

doi:10.54296/18186173_2021_1_43

Авторы

Т.А. Смирнова ФГБУ «ФНИЦ эпидемиологии и микробиологии им. Н.Ф. Гамалеи» МЗ РФ (г. Москва)
Ю.А. Смирнов ФГБУ «ФНИЦ эпидемиологии и микробиологии им. Н.Ф. Гамалеи» МЗ РФ (г. Москва)
В.Г. Жуховицкий ФГБУ «ФНИЦ эпидемиологии и микробиологии им. Н.Ф. Гамалеи» МЗ РФ (г. Москва)

DOI:

https://doi.org/10.54296/18186173_2021_1_43

Ключевые слова:

куркума длинная, куркумин, антибактериальное действие, бактерии

Аннотация

Куркума длинная (Curcuma longa L.) и её биологически активные вещества куркуминоиды обладают плейотропной активностью, включая и антибактериальную активность. Многочисленные исследования показали, что антибактериальная активность экстрактов куркумы и куркуминоидов обладает широким спектром биологических и фармакологических свойств в отношении различных патогенных и условно-патогенных микробов. Механизмы антибактериального действия куркумина состоят либо в прямом вмешательстве в репродукцию бактерий, либо в подавлении клеточных сигнальных путей, необходимых для их репликации. В настоящем обзоре обобщены современные данные и перспективы использования антибактериальной активности куркумина.

Биография автора

Т.А. Смирнова, ФГБУ «ФНИЦ эпидемиологии и микробиологии им. Н.Ф. Гамалеи» МЗ РФ (г. Москва)

Д.б.н., ведущий научный сотрудник лаборатории индикации и ультраструктурного анализа микроорганизмов

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